DESCRIPTION AND HABITAT OF SOME MICRO-ORGANISMS FOUND IN TEGULA FUNEBRALIS Patricia Ann Black Hopkins Marine Station i Ann ology 17 robem in Marine Dr. Phillip: -1- P. Black INTRODUCTION Tegula funebralis (A. Adams, 1854), like many animals, harbors a great many micro-organisms of different types in its digestive tract. Very little is known about these organisms and their relationship to their host, their distribution in the tract, their density and type, and their function within the organism. Galli (1956) describes the eubacteria that he could culture and did intensive studies on the digestive properties of five selected rod-shaped bacteria. He mentioned little about factors of distribution, density, or types actually seen in the digestive tract. This paper deals with the gross properties of the micro-organisms found in the digestive tract of Tegula funebralis, based on examinations of the material found in the lumen as well as on observations of organisms growing on plates. It also deals with one factor of the environment in the digestive tract, namely the hydrogen ion concentration. -2. P. Black MEDIA Two basic types of media were first used. One contained 1.5% agar, 0.1% glucose, 0.05% yeast extract, and 50% sea water; the other contained 1.5% agar, 1.0% 1.0% yeast extract, and 50% sea water. Both O.01% aqueus extract of Tegula funebralis and a similar extract of the alga, Iridaea, were added to some media as a possible growth factor supplement. The enriched media used by Galli (1956 ), salsod, was used. METHODS AND RESULTS Bacteria 1. Density and Distribution. Alimentary contents were examined as wet mounts under a phase contrast microscope to determine type and relative density. This was supplemented by studies of types growing from different parts of the digestive tract on the media. The anterior esophagus showed no obviously motile forms with microscopic examination. Forms resembling cocci were found either singly or in irregular clumps of cells, but were not very numerous. One or two colonies of different types of motile rods appeared on plates. The lower esophagus showed the same kinds of organisms and density under the microscope. The population of bacteria increased sharply in the stomach. The coccus form was very abundant. In addition, -3- P. Black spiral shaped organisms were always found. Sometimes only a few were found in a preparation, sometimes a great number. Where they were numerous, three morpho- logically different types could be distinguished, the dominant one of which was found alone in less numerous preparations. Two forms appear to be spirochaetes and one may be a spirillum. Spirilla were found in great numbers in some preparations. Several different kinds of rods grew in abundance on plates from the stomach. The spiral caecum also has one of the largest populations of bacteria in Tegula funebralis' gut. One can see rods and many cocci. In one animal several spiral forms were also found, although usually this was not the case. Numerous plates were made of spiral caecum material. Many types of motile and non-motile rods were found. A small motile short rod was isolated in large numbers. Numerous colonies of the cocci were also found, but they were extremely small, indicating that they did not thrive under the conditions of culture. The digestive gland contained rods and cocci, some in chains of two or three. Plates showed a concentration of motile rods of the same or similar types. The thin walled hindgut had less bacteria than the midgut area. It contained the same forms in general; in one case it also contained some spirilla and spirochaete forms. Plates revealed a few rods. Motile rods were found in the rectum in good numbers. Spirilla may also be present. -4— P. Black 2. Spiral Forms. The spiral organisms found have not previously been described. Two were thought to be spirochaetes on the basis of their flexibility and tendency to form irregular shapes. Smaller, more rigid forms, with a corkscrew type of motility were distinguished in some cases and thought to be spirilla. They were seen regularly in the stomach and rarely outside. They have never been found anterior to the stomach. Two of the morphologically different types were placed tentatively in the order Spirochaetales (Buchanan, 1918). They belong to the family Spirochaetaceae (Swellengrebel, 1907), being placed there by size. They belong either to the genus Spirochaeta (Ehrenberg, 1833) or the genus Saprospira (Gross, 1911), which are differentiated by Saprospira's periplast membrane and cross striations. These features were difficult to ascertain in an unstained wet mount. One form that was in the minority was seen only rarely. A few cells were found of about the same length as the dominant one, the cell width thinner, with many more waves along the cell. The spirilla form was about half the length of the dominant form and had one to one and a half waves along its body. The dominant type ranged in size from 30 to 70 microns with a mean at about 50 microns. It had 2 to 4 waves with a mean wave length of 15 microns and mean spiral depth -5- P. Black of 7 microns. Yeasts The intestinal contents were examined microscopically for yeast. Yeast cells were observed in medium density in the stomach, in high density with many budding cells in the spiral caecum, and in medium density in the digestive gland. They were only rarely observed in any other part of the digestive tract. Numerous unsuccessful attempts were made to culture these yeasts. Cultures were inoculated from suspensions of the intestinal contents streaked onto plates. The pH of the medium was varied from 4 to 8 in an attempt to discourage bacterial growth and encourage yeast growth. Cultures were incubated botheaerobically and anaerobically. Liquid media were tried in addition to agar plates. In addition, material was streaked on the medium used by Galli (1956 ), who stated that he had obtained five varieties of marine yeast from the intestinal tract of Tegula funebralis. There could be many reasons why no yeasts were observed in culture. The yeast forms so commonly observed may be different from those that Galli (1956 ) isolated. He did not mention how frequently they were isolated. Another relevant factor in this attempt is that the number of micro-organisms in the pieces of the alimentary tract was considerably less than those reported by Galli (1956), as was indicated by two dilution series of -6- P. Black ground intestinal tract prepared in a manner identical to that prepared in his estimates. Environment In order to understand at least one variable of the internal environment of these micro-organisms, attempts were made to measure the hydrogen ion concentration. This was accomplished by dissecting each section of the tract out dry, placing it on a slide, cutting it open, and inserting Nitrazine Paper (E.R. Squibb & Sons). The results are given in Table I. It was not possible, however, to determine the pH of the digestive gland by this method. DISCUSSION Some new information about these micro-organisms has been noted here. The data indicates, first, that most of the micro-organisms are found in the midgut region of the stomach, spiral caecum, and digestive gland. Second, the most abundant organism seen microscopically was a coccus. The role these organisms play in relation to their host is difficult to interpret. It is also difficult to decide whether all represent constant components of the micro¬ organism flora. Some may simply have been ingested by a Tegula funebralis. The constant occurrence of the spiral organisms in large numbers found primarily in the stomach suggests P. Black that they may be regular inhabitants of the digestive tract. Spirochaetes of the genus Cristispira (Gross, 1910) have been described from the intestinal tracts of lamellibranchs. These are fairly large spirochaetes with a characteristic ridge or crista which serves as the axial filament, running longitudinally and making a couple of turns around the body. Their normal habitat is the crystalline style of lamellibranchs, although they have been seen elsewhere in the tract (Bergey's Manual, 1957). They do not appear to harm their hosts (Hawker, et.al; 1960). The Cristispira must have one or several unique requirements, since they usually live isolated from the rest of the gut in the style sac. Their nutritional requirements are unknown. They have never been cultured; in this respect they are like most other spirochaetes, which are very difficult to culture. The spirochaetes in Tegula funebralis may represent similar commensals. They too are reasonably restricted to one part of the digestive tract and live in an area of rich, semi-digested material. The internal environment of Tegula funebralis is very complex. A wide variety of food materials pass through the gut, giving a collection of varied nutrients difficult to access. Another factor, the hydrogen ion concentration, varies over a range of one pH unit and is generally higher than sea water. The bacteria cultured grow well on media ranging in pH from 5.5 to 8.0. -8- P. Black SUMMARY The digestive tract of a gastropod was examined to determine type, location, and density of micro-organisms. Digestive contents were examined microscopically and streaked onto media. The center of density was the stomach, spiral caecum and digestive gland area, where abundant yeast cells were seen and numerous rod-shaped bacteria cultured. Cocci were seen most abundantly throughout, although rarely cultured. Spiral organisms, thought to be two spirochaetes and a spirillum, were found in the stomach and described. The pH of the gut varied from 6.5 to 7.5. Breed, Robert S., E.G.D. Murray and Nathan R. Smith. 1957 Bergey's Manual of Determinative Bacteriology. Baltimore, The Williams & Wilkins Company, xviii + 1094 pp. -8- P. Black SUMMARY The digestive tract of a gastropod was examined to determine type, location, and density of micro-organisms. Digestive contents were examined microscopically and streaked onto media. The center of density was the stomach, spiral caecum and digestive gland area, where abundant yeast cells were seen and numerous rod-shaped bacteria cultured. Cocci were seen most abundantly throughout, although rarely cultured. Spiral organisms, thought to be two spirochaetes and a spirillum, were found in the stomach and described. The pH of the gut varied from 6.5 to 7.5. *. .. Galli, Donald R. 1956 Carbohydrate digestion in a herbivorous marine snail, Tegula funebralis. Masters Thesis, Stanford University, Stanford, California, viii + 153 pp. -8- P. Black SUMMARY The digestive tract of a gastropod was examined to determine type, location, and density of micro-organisms. Digestive contents were examined microscopically and streaked onto media. The center of density was the stomach, spiral caecum and digestive gland area, where abundant yeast cells were seen and numerous rod-shaped bacteria cultured. Cocci were seen most abundantly throughout, although rarely cultured. Spiral organisms, thought to be two spirochaetes and a spirillum, were found in the stomach and described. The pH of the gut varied from 6.5 to 7.5. Hawker, Lilian E., A.H. Linton, B.E. Folkes, and M.J. Carlile. 1960. An Introduction to the Biology of Micro-organisms. London. Edward-Arnold (Publishers) Ltd. 452 pp. -8- P. Black SUMMARY The digestive tract of a gastropod was examined to determine type, location, and density of micro-organisms. Digestive contents were examined microscopically and streaked onto media. The center of density was the stomach, spiral caecum and digestive gland area, where abundant yeast cells were seen and numerous rod-shaped bacteria cultured. Cocci were seen most abundantly throughout, although rarely cultured. Spiral organisms, thought to be two spirochaetes and a spirillum, were found in the stomach and described. The pH of the gut varied from 6.5 to 7.5. Stanier, Roger Y., Michael Doudroff & Edward A. Adelberg. 1963 The Microbial World, Second Edition. Edgewood Cliffs, N.J., Prentice-Hall, Inc., xiii + 753 pp. Table I. P. Black THE HYDROGEN ION CONCENTRATION OF THE ALIMENTARY TRACT OF TEGULA FUNEBRALIS REGION DH 6.5 Mouth 6.5 Anterior esophagus Lower esophagus 6.5 Stomach 6.5 7.0 Spiral caecum 7.0 Anterior hindgut Middle hindgut 6.5 Rectum