Physiology of infected Batallaria J. Miller Pg 2 ABSTRACT: The effects of larval trematode infection on the thermal resistance, respiration rate, rate of Ulva sp. con- sumption and gamete production of Batallaria attramentaria were determined. Nonparasitized snails showed a greater survival rate at 46°0 for 1 hour (.1)p2.05) and at 46°0 for 1 hours (p£.05). The average respiration rates of infected and noninfected snails did not differ significantly. In- dividual respiration rates varied widely in both parasitized and nonparasitized snails. Infected snails consumed more Ulva sp. than uninfected snails (pK.06). No eggs or sperm were observed in heavily infected snails. J. Miller Pg 3 Physiology of infected Batallaria INTRODUCTION Because the host-parasite relationship between molluscs and helminths is longstanding and widespread, (Lauckner, 1980) ecological and physiological studies of the mollusc must con- sider the effects of this parasitism on the host. Some of these effects include cessation of sperm and egg production (Cheng et al., 1965), alterations of digestive-enzyme activity (Marshall et. al., 1974), reduced locomotor activity (Stam- baugh and McDermot, 1969; Tallmark and Narrgren, 1976). Gigantism (Rothschild, 1941), altered migratory habits (Williams and Ellis, 1975), increased food consumption (Wesenberg-Lund, 1934), lowered thermal resistance (Vernberg and Vernberg, 1963) and altered respiration rates (Becker, 1964; Von Brand, 1947; and Vernberg and Vernberg, 1967) have also been reported. With future ecological studies in mind, this study was undertaken to find out the effects of larval trematode in- fection on the thermal resistance, respiration rate, rate of Ulva sp. consumption, and gamete production of the marine mud- flat snail Batallaria attramentaria. MATERIALS AND METHODS After a preliminary survey of larval trematode infection levels in late April, 1980, 2.2 to 2.5 cm in length Batallaria attramentaria were collected from Bennett's Slough, Monterey Bay, J. Miller Pg 4 Physiology of infected Batallaria California, in early May, 1980. Forty-seven per cent of the snails within this population were parasitized with only one undescribed cercaria. The snails were brought into the labo- ratory and held in an aquarium containing mud and Ulva sp. from the slough. Effects of larval trematode infection on the thermal resistance of Batallaria attramentaria were determined by placing snails in individual 50 ml Erlenmyer flasks, which contained 4 paper towel discs, moistened with 2 ml of sea water. Each flask was stoppered with cotton and immersed immediately in a temperature controlled water bath. Snail viability was assayed by placing them, operculum side up, into separate 30 ml beakers, covering them with sea water. If the snail righted itself (i.e. operculum down) within 24 hours it was considered alive. Usually, both infected and uninfected snails right themselves within a few hours and often crawl out of the beakers. Then each snail was dissected and checked for infection. Respiration rates of the snails were measured with a Gilson Differential Respirometer (Gilson Medical Electronics, Middleton, WI.) at a shaking speed of 5 and a temperature of 1690. One snail was placed in each reaction vessel and just covered with sea water. One half ml of 30% KOH was added to the reaction vessel side arm to absorb C0, produced by the snail. After rates were recorded, each snail was removed from its shell, weighed, and checked for infection. Physiology of infected Batallaria J. Miller Pg 5 Effects of parasitism on food consumption were determined by first cutting and weighing 6 cm x 6 cm pieces of Ulva sp. collected from Bennett's slough. One snail, one square of Ulva, and 40 ml of sea water were placed in each of 20, 9 cm x 14 cm, disposable petri dishes. The petri dishes were kept out of direct sunlight in 1 cm deep running sea water. After 10 days the Ulva was weighed and checked for infection. Microscopic observations of the snail gonads were done by preparing thin sections of 3 infected and 3 uninfected snails. Tissues were fixed in a 5% glutaraldehyde, 9% formal- dehyde solution, embedded in JB-4 plastic, cut into 2 u thick sections and stained by the Periodic Acid Schiff method. RESULTS Thermal Resistance The effects of larval trematode infection on Batallaria attramentaria's resistance to thermal stress is shown in Table I. No significant mortality differences were observed at 39°C, 43°C, and 49°C. At 46°0 differences in survival rates were significant at 1 hr (17p2.05) and at 14 hrs (p£.05). After 2 hours at 46 C no differences in survival could be detected. With a 3°0 increase, no snails of either popula- tion survived a 30 minute exposure to 49' C. Physiology of infected Batallaria J. Miller Pg 6 Respiration Rate The average respiration rate of infected snails does not differ significantly from that of uninfected snails (Table II). In both populations there was great variation in individual respiration rates ranging from 24.96 to 122.85 ul O, consumed per gram of snail per hour. In the unin- fected snails and from 38.3 to 121.32 ul 0» consumed per gram of snail per hour in the infected snails. Rate of Ulva sp. Consumption Infected snails had a greater intake of Ulva than unin- fected snails (p(.06) (Table III). Microscopic Observations of Gonad No eggs or sperm were observed in any of the sections of heavily infected snails. Cercaria occupied the gonadal tissue. DISCUS! SION Infection by larval trematodes greatly affects the physiology of Batallaria attramentaria, as shown by the lowered resistance to thermal stress, increased food intake, and lack of gametes in the infected snails. These results concur with those reported by Vernberg and Vernberg (1962) Physiology of infected Batallaria J. Miller Pg 7 and Tallmark and Norrgren (1976) who found thermal resis- tance to be less in other species of parasitized snails. Wesenburg-Lund (1947) has previously shown that infected snails ingest more food and James (1965) has reported cessation of egg and sperm production in Littorina saxatilis. The effect of parasitism on respiration still remains unanswered. Similar average respiration rates for infected and uninfected Batallaria at 16°0 may indicate that the metabolic activity of the larval thermatode is similar to that of the host tissue. With such a wide range of individual rates, however, factors other than just parasitism must be affecting respiration rates. Vernberg and Vernberg (1963) reported differences in respiration rates of parasitized and nonparasitized snails only at temperature extremes of 10°0 and 35°C; Van Brand and Files (1947) found no difference in respiration rates at 30°0; and Beeker (1964) reported a lower respiration rate for infected snails at 25°0. Lower heat resistance, greater intake of food, and absence of gametes in infected snails reduce their resistance to environmental stress. The snail's individual reduced fitness might not be noticeable under slough conditions, but the fitness of the population may be reduced due to parasitic castration. Whitlatch (1974) has reported estimates for population sizes of Batallaria with no mention of the J. Miller Pg 8 Physiology of infected Batallaria effects parasitic castration has on population size. Further studies should include work on the effects of infection on Batallaria's fertility and population fluctuations of the snail and parasite. Physiology of infected Batallaria J. Miller Pg 9 ACKNOWLEDGEMENTS I'd like to thank all the faculty, staff, and students for making spring at HMS a great experience. Special thanks go to Dr. Gary Wagenbach for his patience, his guidance. and an introduction to the Slough; to Dr. Robin Burnett for pointing out the "significance" of my data; to Chris Patton for spending most of his Mondays and more teaching me the fine art of thin sectioning; and to Kathy French for filling all the "Kathy I need this ...' J. Miller Pg 10 Physiology of infected Batallaria LITERATURE CITEI BECKER, W. 1964. Der Einfluss von Trematoden auf den Gastoffwechsel von Stagnicola palustris Mull. 2. ParasiKde 25: 77-102. CHENG, T. C., AND R. W. SNYDER. 1962. Studies on host¬ parasite relationships between larval trematodes and their hosts. I. A review. II. The utilization of the host's glycogen by the intramolluscan larvae of Glypthelmins pennsylvaniensis Cheng, and associated phenomena. Trans Am microsc Soc 81: 209-228. CHENG, T. C., J. T. SULLIVAN, AND K. R. HARRIS. 1973. Parasitic castration of the marine prosobranch gastropod Nassarius obsoletus by sporocysts of Zoogonus rubellus: histopathology. J Invertebr Path 21: 183-190. LAUCKNER, G. 1980. Diseases of mollusca: gastropoda, pp.311- 400 in Otto Kimme, ed. Diseases of Marine Animals. Pitman Press, Bath, Great Britain. MARSHALL, I., D. P. MOMANUS, AND B. L. JAMES. 1974. Phosphomonoesterase activity in intertidal prosobranchs and in their digenean parasites. Comp Biochem Physiol 19 13: 301-306. ROTHSCHILD, M. 1941. Observations on the growth and trematode infections of Peringia ulvae in a pool in the Tamar Saltings, Plymouth. Parasitology 33:406-415. J. Miller Pg 11 Physiology of infected Batallaria STAMBAUGH, J. E. AND J. J. MCDERMOT. 1969. The effects of trematode larvae on the locomotion of naturally in- fected Nassarius obsoletus. Proc Acad nat Sci Philad 43: 226-231. TALLMARK, B. AND G. NORRGREN. 1976. The influence of para- sitic thematodes on the ecology of Nassarius reticu- latus in Gullmar Fjord. zoon 4: 149-156. VERNBERG, W. B. AND F. J. VERNBERG. 1963. Influence of parasitism on thermal resistance of the mud-flat snail, Nassarius obsoletus Say. Expl Parasit 14: 330-332. VERNBERG, W. B. AND F. J. VERNBERG. 1967. Interrelationships between parasites and their hosts. III. Effect of larval thematodes on the thermal metabolic response of their mulluscan host. Expl Parasit 20: 225-231. VON BRAND, T. AND V. S. FILES. 1947. Chemical and histolog- ical observations on the influence of Schistosoma mansoni infection on Australorbis glabratus. J Parasit 33: 476-82. WESENBERG-LUND, C. 1934. Contributions to the development of the Thematoda Digenea. Part II. The biology of the freshwater cercariae in Danish freshwaters. K. danske vidensk. Selsk. Skv. 3: 1-221. WHITLATCH, ROBERT B. 1974. Studies on population ecology of the salt marsh gastropod Batallaria zonalis. Veliger 17: 47-55. Physiology of infected Batallaria J. Miller Pg 12 WILLIAMS. I. C. AND C. ELLIS. 1975. Movements of the common periwinkle, Littorina littorea, on the Yorkshire coast in winter and the influence of infection with larval Pigenea, J exp mar Biol Ecol 33: 413-432. Physiology of infected Batallaria J. Miller Pg 13 Table I: Survival of infected and uninfected Batallaria attramentaria with respect to time and temperature. % Surviving Number of Snails Infected Uninfected Infected Uninfected Temperature — 39°C 100 10 100 6 hours 9 hours 92 12 13 43° 80 88 1 hour 92 2 hours 12 83 3 hours 46° 81 1 hour 41 1.5 hours 18 2 hours 22 3 hours 49° 17 5 hour 0 18 24 1 hour Physiology of infected Batallaria J. Miller Pg 14 Table II: Arithmetic means were calculated from pooled oxygen consumption rates of infected and unin- fected Batallaria attramentaria. UN INFECTED INFECTED ul of O consumed per gram of snail 76 + 25.3 70 + 23.6 per hour (n=29) (n=30) Physiology of infected Batallaria J. Miller Pg 15 Arithmetic means were calculated from pooled Table III: infected and uninfected Batallaria attramentaria rates of Ulva sp. consumption. UNINFECTED INFECTED grams of Ulva sp. consumed 3.2 + 1.1 2.1 +1.3 per gram of snail per 10 days (n=10) (n=10)